Radiesse is a dermal filler used to correct smile lines and nasal-labial folds. Radiesse is a hypo-allergenic product that fills and volumizes wrinkles and lines. Initially, its gel based solution fills the desired area. Radiesse maintains its effect over time as its calcium based microspheres stimulate the body to produce more natural collagen, which our bodies produce less of over time. It generally produces results that last up to one year. Most commonly, it is used to fill lines around the nose, cheeks and chin, and can be used to give volume and fill to the cheekbones.